El Husseini was born in Jerusalem in 1932, and now lives in Paris. She studied fine arts in Beirut and Paris. She had her first exhibit in Paris in 1965, and has since had a number of personal exhibits in the majority of Arab countries, Tokyo, Rome, Amman, Jerusalem. She has also participated in a number of group exhibits such as the Venice Biennial of 1979, the Tokyo Modern Art Museum, and the Museum of Women in the Arts of Washington in 1994. Her works are in numerous private collections around the world. She participated in the French Palestinian spring exhibit at the Paris Institut du Monde Arabe in 1996, and in the 1998 Stockholm Fine Arts Academy “Palestinian Art” exhibit. She is a member of the Sakakini’s General Assembly.